Knowing eosinophils count is our
Eosinophilosophy
What's yours?

Knowing eosinophils count is our
Eosinophilosophy
What's yours?

At GSK, we believe eosinophils count for a lot. They play a role not only in disease, but also in health—and we are committed to better understanding their potential impact on patients’ lives.

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EOS counts in health

Eosinophils may contribute to overall
health and immunoregulation1-3

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EOS counts in disease

Eosinophils contribute to inflammation
and organ damage or dysfunction2,3 

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EOS counts in diagnosis
and treatment decisions

Blood and/or tissue eosinophils can
serve as an important biomarker in
clinical practice4-11 

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References:

  1. Marichal T, Mesnil C, Bureau F. Homeostatic eosinophils: characteristics and functions. Front Med (Lausanne). 2017;4:101.
  2. Travers J, Rothenberg ME. Eosinophils in mucosal immune responses. Mucosal Immunol. 2015;8(3):464-475. 
  3. Klion AD, Ackerman SJ, Bochner BS. Contributions of eosinophils to human health and disease. Annu Rev Pathol. 2020;15:179-209.
  4. Global Initiative for Asthma (GINA). Global strategy for asthma management and prevention. 2021 main report. https://ginasthma.org/gina-reports/. Accessed June 6, 2021.
  5. Global Initiative for Chronic Obstructive Lung Disease (GOLD). Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. 2021 report. https://goldcopd.org/2021-gold-reports/. Accessed June 6, 2021.
  6. Asano K, Hebisawa A, Ishiguro T, et al. New clinical diagnostic criteria for allergic bronchopulmonary aspergillosis/mycosis and its validation. J Allergy Clin Immunol. 2021;147(4):1261-1268.e5.
  7. Wechsler ME. Pulmonary eosinophilic syndromes. Immunol Allergy Clin North Am. 2007;27(3):477-492.
  8. Suzuki Y, Suda T. Eosinophilic pneumonia: A review of the previous literature, causes, diagnosis, and management. Allergol Int. 2019;68(4):413-419.
  9. Masi AT, Hunder GG, Lie JT, et al. The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis). Arthritis Rheum. 1990;33(8):1094-1100.
  10. Reed CC, Dellon ES. Eosinophilic esophagitis. Med Clin North Am. 2019;103(1):29-42.
  11. Valent P, Klion AD, Horny HP, et al. Contemporary consensus proposal on criteria and classification of eosinophilic disorders and related syndromes. J Allergy Clin Immunol. 2012;130(3):607-612.e9.